WebJan 10, 2024 · The half maximal inhibitory concentration (IC50) of different OC cells after treatment with ( a) olaparib, ( b) niraparib and ( c) rucaparib, assessed by clonogenic assays. Data represents the mean ± SEM of triplicates of … WebCisplatin (DDP) is a common therapeutic option for non-small cell lung carcinoma (NSCLC). However, some patients fail to respond to the DDP chemotherapy. Therefore, identifying …
Cisplatin remodels the tumor immune microenvironment via the
WebAfter an incubation with DDP/EXOs, the cell lines exhibited a higher IC50 value for cisplatin, P-gp expression, migration and invasion capabilities and a lower apoptosis … WebBackground: Cisplatin (Cp) is an antineoplastic agent with a dose-limiting nephrotoxicity. Cp-induced nephrotoxicity is characterized by the interplay of oxidative stress, inflammation, and apoptosis. shannon pumphrey little rock arkansas
HCG11 silencing inhibits cisplatin resistance in GC CMAR
WebJun 5, 2024 · E Cell viability of A2780 cells and resistant cells (A2780-CDDP) after were treated with cisplatin at corresponding concentrations for 48 h was detected by CCK-8 assay. Half maximal inhibitory... WebIC50 values were calculated. Evaluation of apoptosis and DNA damage were performed. In addition, the expression of pro-apoptotic and anti-apoptotic genes and proteins were tested. IC50 values indicated less toxicity of the Schiff base … WebFeb 5, 2016 · Cisplatin remains to be primary chemotherapeutic drug for gastric cancer patients, especially for advanced stage ones. However, primary or acquired resistance … shannon purdy