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WebDec 2, 2024 · FO B cells, residing in the lymphoid follicles of the spleen and lymph nodes, comprise the most dominant population of this immune cell. Upon acquiring antigens and interacting with follicular T cells, they proliferate within germinal centers (GC), leading to the production of all antibody isotypes and high-affinity antibodies. WebApr 14, 2024 · Abstract. T-cell receptor (TCR) and B-cell receptor (BCR) repertoire profiling, also referred to as adaptive immune receptor repertoire (AIRR) profiling, holds great potential for the understanding of disease mechanisms and for the development of new treatments in infectious disease, autoimmunity, and immuno-oncology. This potential … popular now on bing burger
Marginal zone, but not follicular B cells, are potent activators of ...
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